HA is a naturally occurring biopolymer that exhibits no species or tissue specificity. Below is an overview of several types of facial injections and implants:. Negative facial reactions were generally mild to moderate in severity and were similar for both Juvederm and Zyplast in terms of duration and frequency, generally lasting for seven days or less. Although the company points out that millions of implants have been used and there have been no allergic reactions,  the absence of objective research on these patients makes these reports questionable. What you need to know is that none of these have been tested long-term and many of them are being used by doctors and consumers in ways that have not been approved of by the Food and Drug Administration FDA.
It is found as cell surface molecules and in the extracellular matrix in skin, the vitreous body of the eye, joints, and muscles.
The Wrinkle in Facial Injections and Implants: Safety Questions
Finally, since many cosmetic injectables are available in Canada, Mexico and elsewhere, patients sometimes leave the country for these procedures or doctors bring them into the United States illegally, making safety claims that are not true. Although the company points out that millions of implants have been used and there have been no allergic reactions,  the absence of objective research on these patients makes these reports questionable. After one year, the ArteFill patients were again evaluated, and showed signs of continued safety and wrinkle correction. The results are not permanent and generally last four or more months. These results will continue to improve over the next few days as the hyaluronic acid is absorbed by the body. There are several techniques that can be utilized for the facial implantation of HA dermal fillers. They are manufactured from an artificially made material that is not biodegradable in the body.